Dosage: Caps/Syp:Adt;250mg-1gm six hourly.Children:125-250mg six hourly Precautions: Hepatic impairment (monitor hepatic funcation, pregnancy. Do not dilute syp below halfstrenght. History of allergy; renal impairment; erythematous rashes common in patients; erythematous rashes common in glandular fever, cytomegalovirus infection, and acute or chronic lymphocytic leukaemia. Streptococcal infection; therapr must be sufficient to eliminates the organism (a minimum of ten days) Otherwise the sequelae of streptococcal disease (endocarditis, rheumatic fever) may occur. Avoid small ineffective doses of penicillin as resistant organisma are more likerly to emerge. Serious and occasionally fatal immediate hypersensitivity (anaphylactoid) reactions have been reported AdverseEffects: Nausea, vomiting, diarrhoea, rashes (discontinue treatment), Rarely antibiotic-associated colitis. Hypersensittivity reactions including urticaria, fever, joint pains, angioedema, anaphylaxis, serum sickness-like reactions, haemolytic anaemia and interstital nephritis (e.g. oligouria, hematuria), neutropenia, thrombocytopenia, coagulation disorders and CNS toxicity including convulsions Indication: Respiratory, ENT and softtissue infection. UTI and gonorrhoea |
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